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Large variation in effects during 10 years of enzyme therapy in adults with Pompe disease.

Harlaar L, Hogrel JY, Perniconi B, Kruijshaar ME, Rizopoulos D, Taouagh N, Canal A, Brusse E, van Doorn PA, van der Ploeg AT, Laforêt P, van der Beek NAME

Neurology, 2019 11 05

Abstract

To determine the effects of 10 years of enzyme replacement therapy (ERT) in adult patients with Pompe disease, focusing on individual variability in treatment response.

doi: 10.1212/WNL.0000000000008441